Publikacje

Abstract:

The application of nano-Ag grains as antiviral and antibacterial materials is widely known
since ancient times. The problem is the toxicity of the bulk or big-size grain materials. It is known
that nano-sized silver grains affect human and animal cells in some medical treatments. The aim
of this study is to investigate the influence of nano-Ag grains embedded in a carbonaceous matrix
on cytotoxicity, genotoxicity in fibroblasts, and mutagenicity. The nanocomposite film is composed
of silver nanograins embedded in a carbonaceous matrix and it was obtained via the PVD method
by deposition from two separated sources of fullerenes and silver acetate powders. This method
allows for the preparation of material in the form of a film or powder, in which Ag nanograins are
stabilized by a carbon network. The structure and morphology of this material were studied using
SEM/EDX, XRD, and Raman spectroscopy. The toxicology studies were performed for various types
of the material differing in the size of Ag nanograins. Furthermore, it was found that these properties,
such as cell viability, genotoxicity, and mutagenicity, depend on Ag grain size.

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Nano-Ag Particles Embedded in C-Matrix: Preparation, Properties and Application in Cell Metabolism